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Dekelver, R.C., Choi, V.M., Moehle, E.A., Paschon, D.E., Hockemeyer, D., Meijsing, S.H., Sancak, Y., Cui, X., Stein, E.J., Miller, J.C., Tam, P., Bartsevich, V.V., Meng, X., Rupniewski, I. Gopalan, S.M. ,Sun, H.C., Pitz, K.J., Rock, J.M., Zhang, L., Davis, G.D., Rebar, E.J., Cheeseman, I.M., Yamamoto, K.R., Sabatini, D.M., Jaenisch, R., Gregory, P.D., Urnov, F.D. (2010) Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome. Genome Res. 20, 1133-42. PDF

Arda H.E., Taubert S., MacNeil, L.T., Conine, C., Tsuda, B., van Gilst, M., Sequerra, R., Doucette-Stamm, L., Yamamoto, K.R., Walhout, A.J.M. (2010) Functional modularity of nuclear hormone receptors in a C. elegans metabolic gene regulatory network. Molecular Systems Biology 6:367. PDF

Taubert, S., Ward, J.D., Yamamoto, K.R. (2010) Nuclear Hormone Receptors in Nematodes: Evolution and Function. Mol. Cell Endcrinol. 334, 49-55. PDF

So, A.L., Bernal, T.U., Pillsbury, M.L., Yamamoto, K.R., Feldman, B.J. (2009) Glucocorticoid Regulation of the Circadian Clock Modulates Glucose Homeostasis. Proc. Natl. Acad. Sci. USA. 106, 17582-7. PDF

Beck, I.M.E., Vanden Berghe, W., Vermeulen, L., Yamamoto, K.R., Haegeman, G.*, De Bosscher, K*. (*share senior authorship) (2009) Crosstalk in Inflammation: The interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases. Endocrine Reviews 30, 830-82. PDF

Jones, J.O., Bolton, E.C., Huang, Y., Feau, C., Guy, R.K., Yamamoto, K.R., Hann, B., Diamond, M.I. (2009) Non-competitive androgen receptor inhibition in vitro and in vivo. Proc Natl Acad Sci USA. 106, 7233-7238. PDF

Meijsing, S.H., Pufall, M.A., So, A.Y., Bates, D.L., Chen, L., Yamamoto, K.R. (2009) DNA-binding site sequence directs glucocorticoid receptor structure and activity. Science 324, 407-410 PDF

Pantoja, C., Huff, J.T., Yamamoto, K.R. (2008) Glucocorticoid Signaling Defines a Novel Commitment State during Adipogenesis In Vitro. Mol. Biol. Cell. 19, 4032-41 PDF

So, A.Y., Cooper, S.B., Feldman, B.J., Manuchehri, M., Yamamoto, K.R. (2008) Conservation Analysis Predicts In Vivo Occupancy of Glucocorticoid Receptor Binding Sequences at Glucocorticoid-Induced Genes. Proc. Natl. Acad. Sci. USA 105; 5745-5749. PDF

Taubert, S., Hansen, M., Van Gilst, M.R., Cooper, S.M., Yamamoto, K.R. (2008) The Mediator Subunit MDT-15 Confers Metabolic Adaptation to Ingested Material. PLoS Genetics 4, e1000021 PDF

Woodruff, P.G., Boushey, H.A., Dolganov, G.M., Barker, C.S., Yang, Y.H., Donnelly, S., Ellwanger, A., Sidhu, S.S., Dao-Pick, T.P., Pantoja, C., Erle, D.J., Yamamoto, K.R., Fahy,. J.V. (2007) Genome-Wide Profiling Identifies Epithelial Cell Genes Associated With Asthma and With Treatment Response to Corticosteroids. Proc. Natl. Acad. Sci. USA 104, 15858-15863. PDF

Bolton, E.C., So, A.Y., Chaivorapol, C., Haqq, C.M., Li, H. and Yamamoto. K.R. (2007) Cell- and Gene-Specific Regulation of Primary Target Genes by the Androgen Receptor. Genes Dev., 21, 2005-2017. PDF

So, A.Y., Chaivorapol, C., Bolton, E.C., Li, H., and Yamamoto, K.R. (2007) Determinants of Cell- and Gene-Specific Transcriptional Regulation by the Glucocorticoid Receptor. PloS Genetics 3, e94. PDF

Ricketson, D., Hostick, U., Fang, L., Yamamoto, K.R., and Darimont, B. A conformational switch in the ligand binding domain regulates the dependence of the glucocorticoid receptor on Hsp90. J. Mol. Biol. 2007 May 4;368(3):729-41. PDF

Meijsing, S.H., Elbi, C., Luecke, H.F., Hager, G.L., and Yamamoto, K.R. (2007) The ligand binding domain controls Glucocorticoid receptor dynamics independent of ligand release. Mol. Cell. Biol. 2007 Apr;27(7):2442-51. PDF

Feldman, B.J., Streeper, R.S., Farese, R.V. Jr. and Yamamoto, K.R.  (2006) Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects. Proc. Natl. Acad. Sci. USA 103, 15675-15680. PDF

Taubert, S., Van Gilst, M.R., Hansen, M., Yamamoto, K.R. (2006) A mediator subunit, MDT-15, integrates regulation of fatty acid metabolism by NHR-49-dependent and-independent pathways in C. elegans. Genes Dev. 20, 1137-1149. PDF

Wang, J-C, Shah, N., Pantoja, C., Meijsing, S.H., Ho, J.D., Scanlan, T.S., Yamamoto, K.R. (2006) Novel arylpyrazole compounds selectively modulate glucocorticoid receptor regulatory activity. Genes Dev. 20, 689-699. PDF

Van Gilst, M.R., Hadjivassiliou, H., and Yamamoto, K.R. (2005)A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. Proc. Natl. Acad. Sci. USA 102, 13496-13501. PDF

Luecke, H.F. and Yamamoto, K.R. (2005). The Glucocorticoid Receptor blocks P-TEFb recruitment by NFkB to effect promoter specific transcriptional repression.  Genes Dev.  19, 1116-1127. PDF

Shostak, Y. and Yamamoto, K.R. (2005) Overlapping but Separable Determinants of DNA Binding and Nuclear Localization Map to the C-terminal End of the C. elegans DAF-12 DNA Binding Domain. J. Biol. Chem. 280, 6554-6560. PDF

Van Gilst, M.R., Hadjivassiliou, H., Jolly, A., and Yamamoto, K.R.  (2005)  Nuclear Hormone Receptor NHR-49 Controls Fat Consumption and Fatty Acid Composition in C. elegansPLoS Biol. 3, e53. PDF

Wang, J-C., Derynck, M.K., Nonaka, D..F, Khodabakhsh, D.B., Haqq, C., Yamamoto, K.R. (2004) Chromatin Immunoprecipitation (ChIP) Scanning Identifies Primary Glucocorticoid Receptor Target Genes. Proc. Natl. Acad. Sci. USA 101, 15603-15608. PDF

**Shostak, Y., Van Gilst, M.R., Antebi, A., and Yamamoto, K.R. (2004). Identification of C. elegans DAF-12 binding sites, response elements and target genes.  Genes Dev. 18, 2529-2544. PDF

Wang, J-C., Walker, A., Blackwell, T.K., and Yamamoto, K.R. (2004) The Caenorhabditis elegans ortholog of TRAP240, CeTRAP240/let-19, selectively modulates gene expression and is essential for embryogenesis. J. Biol. Chem. 279, 29270-29277. PDF

Freedman N.D. and Yamamoto K.R. (2004) Importin 7 and Importin a/Importin beta are Nuclear Import Receptors for the Glucocorticoid Receptor. Mol. Biol. Cell 15, 2276-2286. PDF

Kian Tee, M., Rogatsky, I., Tzagarakis-Foster, C., Cvoro, A., An, J., Christy, R.J., Yamamoto, K.R. and Leitman, D.C. (2004) Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta.  
Mol. Biol. Cell 15, 1262-1272. PDF

Rogatsky, I., Wang, J-C., Derynck, M.K., Nonaka, D., Khodabakhsh, D.B., Haqq, C.M., Darimont, B.D., Garabedian, M.J.,  and Yamamoto, K.R. (2003) Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor
Proc. Natl. Acad. Sci. USA 100, 13845-13850. PDF

Rogatsky, I., Luecke, H.F., Leitman, D.C., Yamamoto, K.R. (2002) Alternate surfaces of transcriptional co-regulator GRIP1 function in different glucocorticoid receptor activation and repression contexts. Proc. Natl. Acad. Sci. USA. 99, 16701-16706. PDF

Freeman, B.C., Yamamoto, K.R.  (2002) Disassembly of transcriptional regulatory complexes by molecular chaperones.  Science 296, 2232-2235. PDF

Rogatsky, I., Zarember, K.A., Yamamoto, K.R.  (2001) Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones.  EMBO J. 20, 6071-6083. PDF

Freeman, B.C., Yamamoto, K.R.  (2001) Continuous recycling: a mechanism for modulatory signal transduction.  Trends Biochem. Sci. 26, 285-290. PDF

van Tilborg, M.A.A., Lefstin, J.A., Kruiskamp, M., Teuben, J., Boelens, R., Yamamoto, K.R., Kaptein, R.  (2000) Mutations in the glucocorticoid receptor DNA-binding domain mimic an allosteric effect of DNA.  J. Mol. Biol. 301, 947-958. PDF

Nissen, R.M., Yamamoto, K.R.  (2000) The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain.  Genes Dev. 14, 2314-2329. PDF

Jamieson, C.A., Yamamoto, K.R.  (2000) Crosstalk pathway for inhibition of glucocorticoid-induced apoptosis by T cell receptor signaling.  Proc. Natl. Acad. Sci. USA. 97, 7319-7324. PDF

Sitcheran, R., Emter, R., Kralli, A., Yamamoto, K.R. (2000) A genetic analysis of glucocorticoid receptor signaling: Identification and characterization of ligand-effect modulators in Saccharomyces cerevisiae.  Genetics 156, 963-972. PDF

Freeman, B.C., Felts, S.J., Toft, D.O., Yamamoto, K.R.  (2000) The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficacies. Genes Dev. 14, 422-434. PDF

Diamond, M.I., Robinson, M.R., Yamamoto, K.R.  (2000) Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor.  Proc. Natl. Acad. Sci. USA 97, 657-661. PDF